Testosterone may be beneficial as a treatment for CAD because testosterone can improve conditions that contribute to heart disease, such as diabetes, obesity, high cholesterol, and triglycerides. Testosterone improves conditions that contribute to heart disease by: dilating the arteries, improving circulation, and lowering blood pressure in most studies (Dubey et al. 2002). Because some people get an increase in blood pressure with testosterone therapy, it is very important to monitor blood pressure. binding to receptors on the arterial wall. Testosterone receptors have been found within human arteries, including aortic, coronary, pulmonary, and carotid arteries, providing evidence that it can affect the arterial wall (Muller et al. 2004). lowering LDL, triglycerides, and Lp(a). activating nitric oxide synthase and, thus, increasing nitric oxide-dependent vasodilatation (Jones, Hugh Jones, and Channer 2004). converting into estrogen via the aromatase enzyme. Normal levels of estrogen may have a beneficial impact on the arterial wall in men. If your total testosterone is normal (say, above 350), your free testosterone may still be low. Make sure to ask for total and free testosterone. If you are borderline low, your doctor may be unwilling to prescribe testosterone. Don’t despair, because there are methods for raising the free level with...