Niacin is very helpful is the control of atherosclerosis when used properly. It lowers bad cholesterol, raises good cholesterol and lowers triglycerides. Its is the most effective agent for increasing cholesterol particle size. Size matters when is comes to what cholesterol particles do in your bloodstream. With proper guidance there are no side effects ti taking niacin. I very rarely see elevated liver enzymes or increased blood sugar. People who are diabetic generally should not take it but may be able to handle a small dose. Studies prove that it can reduce plaque! So, don't be afraid of niacin. Here is a recent study that backs me up here: J Clin Lipidol. 2014 Sep-Oct;8(5):489-93. doi: 10.1016/j.jacl.2014.07.004. Epub 2014 Jul 12. Prolonged combination lipid therapy is associated with reduced carotid intima-media thickness: a case-control study of the 20-year Familial Atherosclerosis Treatment - Observational Study (FATS-OS). Phan BA1, Moore AB2, Davis J2, Pollan LJ2, Neradilek B3, Brown BG2, Zhao XQ2. Author information Abstract BACKGROUND: Studies have documented the short-term vascular benefits of combination lipid therapy. OBJECTIVE: Our objective was to evaluate the long-term effects of combination lipid therapy on carotid intima-media thickness (CIMT) in patients with coronary artery disease. METHODS: We performed a case-control study in patients who had finished...