Category: Integrative Oncology

Capturing the attention of scientists and traditional healers alike, the unassuming coriolus mushroom has a distinctive fan-shaped cap with vibrant rings reminiscent of a turkey’s tail feathers. In fact, it is often called the turkey tail mushroom. Nestled within the heart of forests around the world, several cultures have harnessed the therapeutic potential of these mushrooms and modern science has shed light on their remarkable properties. Emerging studies have delved into the potential role of the main constituents of the coriolus mushroom, including PSK (polysaccharide-K) and PSP (polysaccharide peptide), and show promise as adjunctive therapy to conventional cancer care.   Turkey Tail Mushroom and Overall Cancer Survival A notable feature of coriolus mushrooms is the capacity to increase overall survival in cancer. A systematic review and meta-analysis published in 2019, involving data from 13 randomized control clinical trials and 2,587 patients diagnosed with cancer, demonstrated significant survival advantage for those taking the mushroom adjunctively with standard of care treatment. [[i]] Another review in 2015 evaluated 28 studies and showed improvement of various survival measures, including median, 1-, 2- and 5-year survival, in lung cancer. [[ii]] More specifically, in advanced hepatocellular carcinoma, a small randomized clinical trial involving 15 patients no...

History of Mistletoe Therapy The advent of mistletoe therapy for therapeutic applications in cancer care began to take root in the early 1900’s, pioneered by physicians Rudolf Steiner and Ita Wegman. The ideology of mistletoe stems from the principle of the immune system’s response to fever. Therefore, the goal with mistletoe therapy is to enhance warmth which elucidates an immune system response. This involves identification of unhealthy cells, proliferation of appropriate immune mediators, and induction of direct cytotoxic effects. This mechanism is the reason one might expect a pro-inflammatory response upon administration of mistletoe, such as a slight, transient increase in body temperature and/or fatigue. [[i]]   What is Mistletoe and How is it Used Medically? Mistletoe in its natural form exists as a semi-parasitic plant, inhabiting various types of host trees. The tree in which the mistletoe is derived implies some qualities about the mistletoe that may be useful in cancer care. Other variables influencing the qualitative aspects of the mistletoe include time of harvest and extraction method. Mistletoe is most commonly administered via subcutaneous injection or intravenously. This requires careful consideration from an experienced practitioner to determine the type of mistletoe and route of administration that is preferable...