Coronary heart disease is one of the leading causes of death among both men and women in the United States. Many cardiac patients are choosing to use chelation therapy for heart disease as a form of complementary medicine. But is it safe and effective? Claims of safety concerns caused by low calcium are no longer an issue because disodium EDTA was taken off the market. Disodium EDTA had to be infused slowly because of its effect on blood levels of calcium. We now use calcium EDTA which can be infused very quickly and is very safe. Let’s look at studies examining the effectiveness of chelation with EDTA. EDTA and Chelation Studies Trial to Assess Chelation Therapy (TACT): A clinical trial called the Trial to Assess Chelation Therapy (TACT) attempted to answer the question of safety and effectiveness. This clinical trial, an NIH-sponsored multicenter, double-blind safety and efficacy study, took place from 2002-2012 and was conducted in 134 sites across the United States and Canada. During TACT, 1,708 people, 50+ years old, with previous heart attacks were randomly assigned to receive 40 infusions of a chelation solution or a placebo (inactive) infusion. Research participants also received an oral vitamin and mineral...