Posted By:
Kelly Parcell
Category:
General
Bisphosphonates are used in the treatment of low calcium states, such as Osteopenia/osteoporosis. Bisphosponates such as Fosamax, Boniva, Actonel are examples of this class of drugs. Years ago studies began to show that these drugs actually caused bisphosphonate osteonecrosis of the jaw. Osteonecrosis is a fancy word for cellular death of bone tissue. Studies have shown that this happens because these medications so commonly prescribed for women with low bone density, actually affect methylation in our DNA. Effects of bisphosphonate treatment on DNA methylation in osteonecrosis of the jaw. Polidoro S, Broccoletti R, Campanella G, Di Gaetano C, Menegatti E, Scoletta M, Lerda E, Matullo G, Vineis P, Berardi D, Scully C, Arduino PG. Mutat Res. 2013 Jul 24. pii: S1383-5718(13)00203-9. doi: 10.1016/j.mrgentox.2013.07.003. [Epub ahead of print] Methylation is an important chemical process that occurs in the body. It is an important process in detoxification, protein function, DNA expression, blood clotting, and more. A simple truth is that folic acid is involved in this process and not just any folic acid, but the active form of folic acid called 5tetrahydrofolate folic acid. In otherwords, in order for folic acid to function effectively in the body, it must be 'activated'. The...