Posted By:
Steve Parcell
Category:
Preventive Cardio
Many of us involved in extending life span and preventing disease are very excited about rapamycin right now. This is because low-dose rapamycin can slow, or even reverse aging. It is the best thing we have to date when it comes to extending life span. There is considerable research in motion on rapamycin and its role in human disease. I am particularly interested in its role in cardiovascular prevention, especially in reversing arterial disease and heart disease. What is Rapamycin and How Does it Work? Rapamycin was discovered on Easter Island in 1965. It is made by a bacterium called Streptomyces hygroscopicus and was first used as an antifungal. Because it is a naturally occurring compound it is a naturopathic medicine. It is now used in conventional medicine to prevent organ rejection, after vascular surgery, and as a cancer treatment. There can be considerable side effects of rapamycin with the high doses given for these conditions. The lower doses used for cardiovascular prevention and aging mean that side effects are rare. The treatment of middle-aged mice with a rapamycin has been shown to extend lifespan and reduce several age associated diseases. Rapamycin works by inhibiting mTOR, a protein that regulates...