Category: Integrative Cancer Support

According to this Harvard researcher higher testosterone may be protective against prostate cancer and low levels may increase risk. I have to say that in my experience this is true. Steve Parcell, RND, ND  

STUDY: J Transl Med. 2017 Apr 14;15(1):77. doi: 10.1186/s12967-017-1179-7. The role of vitamin C in the treatment of pain: new insights. Carr AC(1), McCall C(2). Author information: (1)Department of Pathology, University of Otago, Christchurch, PO Box 4345, Christchurch, 8140, New Zealand. anitra.carr@otago.ac.nz. (2)Centre for Postgraduate Nursing Studies, University of Otago, Christchurch, PO Box 4345, Christchurch, 8140, New Zealand. The vitamin C deficiency disease scurvy is characterised by musculoskeletal pain and recent epidemiological evidence has indicated an association between suboptimal vitamin C status and spinal pain. Furthermore, accumulating evidence indicates that vitamin C administration can exhibit analgesic properties in some clinical conditions. The prevalence of hypovitaminosis C and vitamin C deficiency is high in various patient groups, such as surgical/trauma, infectious diseases and cancer patients. A number of recent clinical studies have shown that vitamin C administration to patients with chronic regional pain syndrome decreases their symptoms. Acute herpetic and post-herpetic neuralgia is also diminished with high dose vitamin C administration. Furthermore, cancer-related pain is decreased with high dose vitamin C, contributing to enhanced patient quality of life. A number of mechanisms have been proposed for vitamin C's analgesic properties. Herein we propose a novel analgesic mechanism for vitamin C; as...

In a recent study on intravenous vitamin C for cancer levels of tumour markers and proinflammatory cytokines decreased. This indicated treatment effectiveness.  STUDY: Med Sci Monit. 2016 Jan 3;22:14-25. Modulation of Cytokines in Cancer Patients by Intravenous Ascorbate Therapy. Mikirova N(1), Riordan N(2), Casciari J(3). Author information: (1)Bio-Communication research institute, Riordan Clinic, Wichita, KS, USA. (2)Amniotic Therapies, Dallas, TX, USA. (3)Research Consultant, Riordan Clinic, Wichita, KS, USA. BACKGROUND: Cytokines play an important role in tumor angiogenesis and inflammation. There is evidence in the literature that high doses of ascorbate can reduce inflammatory cytokine levels in cancer patients. The objective of this study was to investigate the effect of treatment by intravenous vitamin C (IVC) on cytokines and tumor markers. MATERIAL/METHODS: With the availability of protein array kits allowing assessment of many cytokines in a single sample, we measured 174 cytokines and additional 54 proteins and tumor markers in 12 cancer patients before and after a series of IVC treatments. RESULTS: Presented results show for our 12 patients the effect of treatment resulted in normalization of many cytokine levels. Cytokines that were most consistently elevated prior to treatments included M-CSF-R, Leptin, EGF, FGF-6, TNF-α, β, TARC, MCP-1,4, MIP, IL-4, 10, IL-4,...

Extracorporeal photopheresis (ECP) is a type of ultraviolet blood irradiation that is being studies extensively right now for a variety of conditions such as cancer, infections, pain and inflammation. As we noted earlier we are enrolling patients in a study on this treatment. STUDY: Photodermatol Photoimmunol Photomed. 2015 Jul;31(4):184-94. doi: 10.1111/phpp.12175. Epub 2015 Mar 28. The effect of extracorporeal photopheresis alone or in combination therapy on circulating CD4(+) Foxp3(+) CD25(-) T cells in patients with leukemic cutaneous T-cell lymphoma. Shiue LH(1,)(2), Couturier J(3,)(4), Lewis DE(3,)(4), Wei C(5), Ni X(1,)(2), Duvic M(1,)(2). Author information: (1)Department of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (2)Graduate Program in Immunology, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA. (3)Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA. (4)Graduate Program in Virology, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA. (5)Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. PURPOSE: Extracorporeal photopheresis (ECP) alone or in combination therapy is effective for treatment of leukemic cutaneous T-cell lymphoma (L-CTCL), but its mechanism(s) of action remain...

Metformin is a drug that is used primarily to lower blood sugar in prediabetes or diabetes. In recent years research continues to show benefits for arresting cancer cell growth as well.  Metformin affects multiple key processes related to cell growth, proliferation, and survival through a number rof pathways. Metformin decreases the amount of glucose produced by the liver and reduces the bloodstream level and cellular uptake of insulin. The reduced insulin stimulation results in reduced activation of insulin receptors on cell membranes, triggering a cascade of intracellular molecular pathways that may be activated in different types of cancer cells. At this point we recommend it to most cancer patients.