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Category: Integrative Cancer Support

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    NatureMed Oncology

  • Category:

    Integrative Cancer Support

Dr. Kirsten West, RND, ND, LAc, FABNO has recently co-authored an article about Treating Cancer with Curcumin. Below you can read the abstract and view the complete article in PDF format. Abstract Oncologists tend to avoid the use of supplements during chemotherapy. To understand the safety issue, a literature review was conducted to evaluate the safety and possible benefits of taking curcumin during chemotherapy. Curcumin was chosen because of its wide use in the public and because of the availability of clinical trials utilizing curcumin during chemotherapy. Curcumin is considered a “pan-assay interference compound,” creating false leads in drug discovery assays. The pharmacodynamics of curcumin presents many challenges for a therapeutic agent, including poor bioavailability and rapid q metabolism and excretion. The proposed molecular targets for curcumin include inhibition of nuclear factor kappa B and inhibition of cyclooxygenase-2.  Clinical trials investigating the efficacy of curcumin treatment for cancer have been conducted in patients with colorectal cancer (CRC), pancreatic cancer, breast cancer, prostate cancer, multiple myeloma, lung cancer, and head and neck cancer.  Outcomes revealed that while curcumin was not effective,  it was well tolerated and safe. Recently, there have been several Phase I and Phase II trials combining curcumin with chemotherapeutic agents. Two trials investigated the...

  • Posted By:

    NatureMed Oncology

  • Category:

    Integrative Cancer Support

Below an abstract from medical liturature on the benefits of mistletoe on chemotherapy resistant lung cancer cells. Phytomedicine. 2017 Dec 1;36:183-193. doi: 10.1016/j.phymed.2017.09.017. Epub 2017 Sep 29. Mistletoe (Viscum album) extract targets Axl to suppress cell proliferation and overcome cisplatin- and erlotinib-resistance in non-small cell lung cancer cells. Kim S1, Kim KC2, Lee C3. Author information Abstract BACKGROUND: Mistletoe extract of Visucm album extract (VAE) contains many biologically active components and has been reported to be not only a complementary and alternative medicine, but also a potent therapeutic agent for many types of cancer. PURPOSE: In this study, we examined the effect of VAE on expression and activation of Axl and scrutinized the involvement of Axl in the anti-cancer activity of VAE in parental and chemo-resistant non-small cell lung cancer (NSCLC) cells. METHODS: The levels of Axl protein and mRNA were determined by Western blot analysis and RT-PCR, respectively. Phosphorylation of Axl upon Gas6 stimulation was observed by Western blot analysis. For ectopic expression or gene silencing of Axl, the recombinant plasmid, pcDNA3-Axl, or specific siRNA targeting Axl were transfected into A549 and H460 cells using Lipofectamine 2000, respectively. The anti-cancer activity of mistletoe extract was examined against the parental cells and each of their cisplatin- or...

  • Posted By:

    NatureMed

  • Category:

    Integrative Cancer Support

According to this Harvard researcher higher testosterone may be protective against prostate cancer and low levels may increase risk. I have to say that in my experience this is true. Steve Parcell, RND, ND  

  • Posted By:

    NatureMed

  • Category:

    Integrative Cancer Support

STUDY: J Transl Med. 2017 Apr 14;15(1):77. doi: 10.1186/s12967-017-1179-7. The role of vitamin C in the treatment of pain: new insights. Carr AC(1), McCall C(2). Author information: (1)Department of Pathology, University of Otago, Christchurch, PO Box 4345, Christchurch, 8140, New Zealand. anitra.carr@otago.ac.nz. (2)Centre for Postgraduate Nursing Studies, University of Otago, Christchurch, PO Box 4345, Christchurch, 8140, New Zealand. The vitamin C deficiency disease scurvy is characterised by musculoskeletal pain and recent epidemiological evidence has indicated an association between suboptimal vitamin C status and spinal pain. Furthermore, accumulating evidence indicates that vitamin C administration can exhibit analgesic properties in some clinical conditions. The prevalence of hypovitaminosis C and vitamin C deficiency is high in various patient groups, such as surgical/trauma, infectious diseases and cancer patients. A number of recent clinical studies have shown that vitamin C administration to patients with chronic regional pain syndrome decreases their symptoms. Acute herpetic and post-herpetic neuralgia is also diminished with high dose vitamin C administration. Furthermore, cancer-related pain is decreased with high dose vitamin C, contributing to enhanced patient quality of life. A number of mechanisms have been proposed for vitamin C's analgesic properties. Herein we propose a novel analgesic mechanism for vitamin C; as...

  • Posted By:

    NatureMed

  • Category:

    Integrative Cancer Support

In a recent study on intravenous vitamin C for cancer levels of tumour markers and proinflammatory cytokines decreased. This indicated treatment effectiveness.  STUDY: Med Sci Monit. 2016 Jan 3;22:14-25. Modulation of Cytokines in Cancer Patients by Intravenous Ascorbate Therapy. Mikirova N(1), Riordan N(2), Casciari J(3). Author information: (1)Bio-Communication research institute, Riordan Clinic, Wichita, KS, USA. (2)Amniotic Therapies, Dallas, TX, USA. (3)Research Consultant, Riordan Clinic, Wichita, KS, USA. BACKGROUND: Cytokines play an important role in tumor angiogenesis and inflammation. There is evidence in the literature that high doses of ascorbate can reduce inflammatory cytokine levels in cancer patients. The objective of this study was to investigate the effect of treatment by intravenous vitamin C (IVC) on cytokines and tumor markers. MATERIAL/METHODS: With the availability of protein array kits allowing assessment of many cytokines in a single sample, we measured 174 cytokines and additional 54 proteins and tumor markers in 12 cancer patients before and after a series of IVC treatments. RESULTS: Presented results show for our 12 patients the effect of treatment resulted in normalization of many cytokine levels. Cytokines that were most consistently elevated prior to treatments included M-CSF-R, Leptin, EGF, FGF-6, TNF-α, β, TARC, MCP-1,4, MIP, IL-4, 10, IL-4,...