Intravenous (IV) vitamin C was studied in patients with breast cancer who were treated with chemotherapy and radiation therapy. The study found that patients who received IV vitamin C had better quality of life and fewer side effects than those who did not. A study of IV vitamin C was done in patients with cancer that were not responding to conventional treatment. Vitamin C was shown to be a safe and effective therapy to improve physical, mental, and emotional functions. Symptoms of fatigue, nausea and vomiting, pain, and appetite loss all got better.
In a small study of patients with advanced pancreatic cancer, IV vitamin C was given along with chemotherapy and treatment with a targeted therapy. Patients had very few bad side effects from the vitamin C treatment. The nine patients who completed the treatment had stable disease as shown by imaging studies. In another small study of 9 patients with advanced pancreatic cancer, patients were given chemotherapy in treatment cycles of once per week for 3 weeks along with IV vitamin C twice per week for 4 weeks. These patients had disease that did not progress for a period of months. The combined treatment was well tolerated and no serious side effects were reported.